Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/71706
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Type: Journal article
Title: Timing of colonization of caries-producing bacteria: an approach based on studying monozygotic twin pairs
Author: Bockmann, M.
White, A.
Bennett, C.
Odeh, R.
Hughes, T.
Townsend, G.
Citation: International Journal of Dentistry, 2011; 2011(571573):1-7
Publisher: Hindawi Publishing Corporation
Issue Date: 2011
ISSN: 1687-8728
1687-8736
Statement of
Responsibility: 
Michelle R. Bockmann, Abbe V. Harris, Corinna N. Bennett, Ruba Odeh, Toby E. Hughes and Grant C. Townsend
Abstract: Findings are presented from a prospective cohort study of timing of primary tooth emergence and timing of oral colonization of Streptococcus mutans (S. mutans) in Australian twins. The paper focuses on differences in colonization timing in genetically identical monozygotic (MZ) twins. Timing of tooth emergence was based on parental report. Colonization timing of S. Mutans were established by plating samples of plaque and saliva on selectivemedia at 3monthly intervals and assessing colony morphology. In 25% of individuals colonization occurred prior to emergence of the first tooth. A significant proportion ofMZ pairs (21%) was discordant for colonization occurring before or after first tooth emergence, suggesting a role of environmental or epigenetic factors in timing of tooth emergence, colonization by S. mutans, or both. These findings and further application of theMZ co-twin model should assist in development of strategies to prevent or delay infection with S. mutans in children.
Description: Extent: 7p.
Rights: Copyright © 2011 Michelle R. Bockmann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
RMID: 0020117446
DOI: 10.1155/2011/571573
Appears in Collections:Dentistry publications

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