Adelaide Research & Scholarship
Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/74682
| Type: | Patent |
| Title: | Altered Insulin-Like Growth Factor binding Proteins |
| Author: | Forbes, B. |
| Issue Date: | 2009 |
| Assignee: | University of Adelaide |
| Contributor: | Foley & Lardner LLP |
| Statement of Responsibility: | Inventor B. Forbes; Assigned to University of Adelaide; Foley & Lardner LLP agents for inventor. |
| Abstract: | Altered IGFBPs are able to bind IGF, but the release is inhibited by resistance to protease cleavage and/or reduced binding to extracellular matrix (ECM). Alterations have been made in IGFBP-2 to the linker domain in particular and to two amino acid motifs found to be important for ECM binding. IGF-1 mediated proliferation of cancer cells have been inhibited by use of the altered IGFBPs. |
| Keywords: | US 7488798 PCT/AU03/00898 |
| Description: | PATENT: B. Forbes (Assignee: University of Adelaide). US 7488798 (PCT/AU03/00898) filed Jul 11, 2003; published Feb 10, 2009; predicted expiry Jul 11, 2023. |
| Patent #: | 7488798 |
| Description (link): | http://www.patentlens.net/patentlens/patent/US_7488798/en/ |
| Appears in Collections: | Aurora harvest 4 Molecular and Biomedical Science publications |
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