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https://hdl.handle.net/2440/76533
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Type: | Journal article |
Title: | Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera |
Author: | Baxter, S. Badenes-Perez, F. Morrison, A. Vogel, H. Crickmore, N. Kain, W. Wang, P. Heckel, D. Jiggins, C. |
Citation: | Genetics: a periodical record of investigations bearing on heredity and variation, 2011; 189(2):675-679 |
Publisher: | Genetics |
Issue Date: | 2011 |
ISSN: | 0016-6731 1943-2631 |
Statement of Responsibility: | Simon W. Baxter, Francisco R. Badenes-Pérez, Anna Morrison, Heiko Vogel, Neil Crickmore, Wendy Kain, Ping Wang, David G. Heckel, and Chris D. Jiggins |
Abstract: | Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function. |
Keywords: | Animals Lepidoptera Moths Bombyx Bacterial Proteins Multidrug Resistance-Associated Proteins Insect Proteins Endotoxins Chromosome Mapping Sequence Analysis, DNA Evolution, Molecular Phylogeny Species Specificity Synteny Insecticide Resistance Mutation Molecular Sequence Data Female Male Hemolysin Proteins Genetic Variation Chromosomes, Insect Bacillus thuringiensis Toxins |
Rights: | Copyright © 2011 by the Genetics Society of America |
DOI: | 10.1534/genetics.111.130971 |
Appears in Collections: | Aurora harvest Environment Institute publications Molecular and Biomedical Science publications |
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