Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/76533
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Type: Journal article
Title: Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera
Author: Baxter, S.
Badenes-Perez, F.
Morrison, A.
Vogel, H.
Crickmore, N.
Kain, W.
Wang, P.
Heckel, D.
Jiggins, C.
Citation: Genetics: a periodical record of investigations bearing on heredity and variation, 2011; 189(2):675-679
Publisher: Genetics
Issue Date: 2011
ISSN: 0016-6731
1943-2631
Statement of
Responsibility: 
Simon W. Baxter, Francisco R. Badenes-Pérez, Anna Morrison, Heiko Vogel, Neil Crickmore, Wendy Kain, Ping Wang, David G. Heckel, and Chris D. Jiggins
Abstract: Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.
Keywords: Animals
Lepidoptera
Moths
Bombyx
Bacterial Proteins
Multidrug Resistance-Associated Proteins
Insect Proteins
Endotoxins
Chromosome Mapping
Sequence Analysis, DNA
Evolution, Molecular
Phylogeny
Species Specificity
Synteny
Insecticide Resistance
Mutation
Molecular Sequence Data
Female
Male
Hemolysin Proteins
Genetic Variation
Chromosomes, Insect
Bacillus thuringiensis Toxins
Rights: Copyright © 2011 by the Genetics Society of America
DOI: 10.1534/genetics.111.130971
Published version: http://dx.doi.org/10.1534/genetics.111.130971
Appears in Collections:Aurora harvest
Environment Institute publications
Molecular and Biomedical Science publications

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