Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/78413
Type: | Journal article |
Title: | Integration of enzyme immobilised single-walled carbon nanotube arrays into microchannels for glucose detection |
Author: | Yu, J. Matthews, S. Yunus, K. Shapter, J. Fisher, A. |
Citation: | International Journal of Electrochemical Science, 2013; 8(2):1849-1862 |
Publisher: | Electrochemical Science Group |
Issue Date: | 2013 |
ISSN: | 1452-3981 1452-3981 |
Statement of Responsibility: | Jingxian Yu, Sinéad M Matthews, Kamran Yunus, Joseph G Shapter and Adrian C Fisher |
Abstract: | Microfluidic devices for glucose detection have been constructed and developed by integration of covalently immobilised single-walled carbon nanotube arrays functionalised with glucose oxidase into a poly (dimethylsiloxane)-based microfluidic channel. With biocompatible ferrocenecarboxylic acid as electron transfer mediator, these microfluidic devices were tested systematically for electrochemical glucose detection by changing some geometrical parameters such as the width of detecting electrode as well as electrode gap between the enzyme electrode and the detecting electrode. Numerical simulations were also carried out using a finite difference model and used to further understand the concentration profiles in michochannels. The experimental results showed that glucose can be detected with a linear response up to a concentration of 5 mmol L⁻¹. Compared to reported glucose detection techniques, our microfluidic devices have some advantages such as simple design, repeated use and low cost. |
Keywords: | Microfluidic devices glucose oxidase carbon nanotube arrays glucose detection ferrocenecarboxylic acid |
Rights: | © 2013 by ESG (www.electrochemsci.org) |
Grant ID: | http://purl.org/au-research/grants/arc/DP0985176 http://purl.org/au-research/grants/arc/DP0985176 |
Published version: | http://www.electrochemsci.org/papers/vol8/80201849.pdf |
Appears in Collections: | Aurora harvest IPAS publications |
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