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|Title:||Characterisation of novel and rare Y-chromosome short tandem repeat alleles in self-declared South Australian Aboriginal database|
van Oorschot, R.
|Citation:||International Journal of Legal Medicine, 2014; 128(1):27-31|
|Tegan E. Collins, Renee Ottens, Kaye N. Ballantyne, Nano Nagle, Julianne Henry, Duncan Taylor, Michael G. Gardner, Alison J. Fitch, Amanda Goodman, Roland A. H. van Oorschot, R. John Mitchell, Adrian Linacre|
|Abstract:||Y-chromosome short tandem repeats (Y-STRs) are used in forensic science laboratories all over the world, as their application is wide and often vital in solving casework. Analysis of an in-house database of South Australian self-declared Aboriginal males held by Forensic Science South Australia (FSSA) using the Applied Biosystem’s AmpFℓSTR® Yfiler™ PCR Amplification Kit revealed 43 variant Y-STR alleles at 6 of the 17 loci. All variant alleles were sequenced to determine the exact repeat structure for each. As a high level of admixture has previously been found within the SA Aboriginal database, samples were haplogrouped using Y-SNPs to determine their likely geographical origin. Although a number of variant alleles were associated with non-Aboriginal Y-haplogroups, a high frequency was observed within the Australian K-M9 lineage. Detailed knowledge of these variant alleles may have further application in the development of new DNA markers for identification purposes, and in population and evolutionary studies of Australian Aborigines.|
Australian Aboriginal males
|Rights:||© Springer-Verlag Berlin Heidelberg 2013|
|Appears in Collections:||Aurora harvest 4|
Molecular and Biomedical Science publications
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