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Type: Journal article
Title: Antibody response to pneumococcal vaccine in children aged 5 to 15 years
Author: Paton, J.C.
Toogood, I.R.
Cockington, R.A.
Hansman, D.
Citation: American journal of diseases of children (1960), 1986; 140(2):135-138
Publisher: American Medical Association
Issue Date: 1986
ISSN: 0002-922X
Statement of
James C. Paton, Ian R. Toogood, Richard A. Cockington, David Hansman
Abstract: The type-specific antibody response of 99 healthy children, aged 5 to 15 years, to a 14-valent pneumococcal vaccine was determined and analyzed according to age at the time of vaccination. The response to the majority of the serotypes, including the important "pediatric" types 6A, 18C, and 19F, appeared to plateau in the 8- to 10-year-old age group, whereas for types 14 and 23F, which are also important in children, the response continued to improve with age to ages 13 to 15 years. The antibody response of a group of 23 children, aged 5 to 15 years, with various hematologic disorders (12 of whom had undergone splenectomy) was also determined and compared with that of the healthy children. For all serotypes the antibody response was similar in the two groups.
Keywords: Humans
Streptococcus pneumoniae
Hematologic Diseases
Age Factors
Antibody Formation
Child, Preschool
Rights: Copyright status unknown
DOI: 10.1001/archpedi.1986.02140160053031
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Appears in Collections:Aurora harvest 2
Molecular and Biomedical Science publications

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