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Type: Journal article
Title: Comparative genome analysis of a Saccharomyces cerevisiae wine strain
Author: Borneman, A.
Forgan, A.
Pretorius, I.
Chambers, P.
Citation: FEMS Yeast Research, 2008; 8(7):1185-1195
Publisher: Wiley
Issue Date: 2008
ISSN: 1567-1356
Statement of
Anthony R. Borneman, Angus H. Forgan, Isak S. Pretorius and Paul J. Chambers
Abstract: Many industrial strains of Saccharomyces cerevisiae have been selected primarily for their ability to convert sugars into ethanol efficiently despite exposure to a variety of stresses. To begin investigation of the genetic basis of phenotypic variation in industrial strains of S. cerevisiae, we have sequenced the genome of a wine yeast, AWRI1631, and have compared this sequence with both the laboratory strain S288c and the human pathogenic isolate YJM789. AWRI1631 was found to be substantially different from S288c and YJM789, especially at the level of single-nucleotide polymorphisms, which were present, on average, every 150 bp between all three strains. In addition, there were major differences in the arrangement and number of Ty elements between the strains, as well as several regions of DNA that were specific to AWRI1631 and that were predicted to encode proteins that are unique to this industrial strain.
Keywords: genome sequence; Saccharomyces cerevisiae; wine yeast
Description: Article first published online: 5 SEP 2008
Rights: © 2008 Federation of European Microbiological Societies
DOI: 10.1111/j.1567-1364.2008.00434.x
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Appears in Collections:Aurora harvest 7
Molecular and Biomedical Science publications

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