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Type: Patent
Title: Systematic evolution of ligands by exponential enrichment: tissue selex
Author: Chen, H.
Gold, L.
Jensen, K.B.
Morris, K.N.
Stephens, A.
Issue Date: 1998
Assignee: NeXstar Pharmaceuticals, Inc.
Contributor: Swanson & Bratschun. LLC
Swanson & Bratschun. LLC
Statement of
Inventors: Jensen; Kirk B., Chen; Hang, Morris; Kevin N., Stephens; Andrew, Gold; Larry. Assignee: Nexstar Pharmaceuticals, Inc. Agents: Swanson & Bratschun. LLC
Abstract: This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.
Description: Publication number US5789157 A Publication type Grant Application number US 08/434,425 Publication date Aug 4, 1998 Filing date May 3, 1995 Priority date Jun 11, 1990
Patent #: US5789157 A
RMID: 0030016415
Appears in Collections:Molecular and Biomedical Science publications

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