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https://hdl.handle.net/2440/57954
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Type: | Journal article |
Title: | Elevated serum concentrations of troponin T in acute stroke: What do they mean? |
Author: | Ghali, J. Allison, D. Kleinig, T. Ooi, S. Bastiampillai, S. Ashby, D. Taylor, J. Thompson, P. Broadley, S. |
Citation: | Journal of Clinical Neuroscience, 2010; 17(1):69-73 |
Publisher: | Churchill Livingstone |
Issue Date: | 2010 |
ISSN: | 0967-5868 1532-2653 |
Statement of Responsibility: | Joanna Ghali, Dale Allison, Timothy Kleinig, Soon Yen Ooi, Shalini Bastiampillai, Dale Ashby, James Taylor, Philip D. Thompson and Simon A. Broadley |
Abstract: | Elevations in serum troponin T in acute stroke have been suggested as an early marker of a poor outcome. A prospective, case-control study was undertaken to define characteristics associated with elevations in troponin T concentrations. Consecutive admissions to the Royal Adelaide stroke unit were assessed. Stroke outcome was determined using the modified Rankin scale. Elevated serum troponin T was seen in 12/109 (11%) of patients with stroke and was associated with more severe stroke, larger lesion volume and a worse outcome. However, as a prognostic indicator, elevations in troponin T had lower sensitivity for predicting death or dependence at discharge than the National Institute of Health Stroke Scale. Troponin T levels are elevated in a significant proportion of patients with acute stroke, principally those with large infarcts affecting the territory supplied by the middle cerebral artery but their value as a prognostic indicator remains uncertain. |
Keywords: | Case-control study Cerebrovascular accident Cerebral infarction Prognosis Stroke Troponin T |
Rights: | Crown copyright © 2009 Published by Elsevier Ltd. |
DOI: | 10.1016/j.jocn.2009.03.017 |
Published version: | http://dx.doi.org/10.1016/j.jocn.2009.03.017 |
Appears in Collections: | Aurora harvest 5 Medicine publications |
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