Pharmacology
Permanent URI for this community
Browse
Browsing Pharmacology by Author "Adlington, R.M."
Now showing 1 - 1 of 1
Results Per Page
Sort Options
Item Metadata only Biomimetic synthetic studies on meroterpenoids from the marine sponge Aka coralliphaga: divergent total syntheses of siphonodictyal B, liphagal and corallidictyals A–D(Elsevier, 2019) Kuan, K.K.W.; Markwell-Heys, A.W.; Cruickshank, M.C.; Tran, D.P.; Adlington, R.M.; Baldwin, J.E.; George, J.H.The marine sponge Aka coralliphaga is a rich source of biologically active and structurally interesting meroterpenoids. Inspired by these natural products, we have used biosynthetic speculation to devise biomimetic syntheses of siphonodictyal B, liphagal and corallidictyals A-D from sclareolide. This work resulted in the development of new cascade reactions in the synthesis of liphagal, the reassignment of the structure of siphonodictyal B, and the realisation that corallidictyals A and B are possibly isolation artefacts.