General Practice

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The Discipline of General Practice is part of the School of Population Health and Clinical Practice

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Browsing General Practice by Author "Alati, R."

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    Association of maternal smoking and alcohol consumption with young adults' cannabis use: A prospective study
    (Oxford Univ Press Inc, 2007) Hayatbakhsh, M.; Alati, R.; Hutchinson, D.; Jamrozik, K.; Najman, J.; Mamun, A.; O'Callaghan, M.
    This 2006 study examined 1) whether maternal use of tobacco and consumption of alcohol when a child is 5 and 14 years of age predict cannabis use in young adults, and 2) whether this association is explained by possible confounding or mediating factors. Data were taken from a prospective birth cohort study of mothers and their children in Brisbane, Australia. This study was based on a cohort of 3,176 young adults who participated at the 21-year follow-up of the study and for whom data were available on maternal smoking and alcohol consumption 5 and 14 years after their birth. After controlling for possible confounders, the authors found that maternal smoking at 14 years was associated with frequent use of cannabis in offspring at 21 years, regardless of maternal smoking at 5 years. Children of mothers who drank more than one glass of alcohol at 5 years and continued at 14 years were more likely to use cannabis in early adulthood. The association between maternal substance use and offspring cannabis use was partially mediated by adolescent externalizing behavior and smoking measured at 14 years. Prevention programs that address maternal and adolescent tobacco use and adolescent externalizing behavior should be considered as strategies to reduce cannabis use by young adults.
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    Cannabis and anxiety and depression in young adults: A large prospective study
    (Lippincott Williams & Wilkins, 2007) Hayatbakhsh, M.; Najman, J.; Jamrozik, K.; Mamun, A.; Alati, R.; Bor, W.
    OBJECTIVE: To examine whether age of first use or frequency of use of cannabis is associated with anxiety and depression (AD)in young adults, independent of known potential confounders, including the use of other illicit drugs. METHOD: A cohort of 3,239 Australian young adults was followed from birth to the age of 21 when data on AD were obtained from sample members along with information on their use of cannabis at 21 years. Potential confounding factors were prospectively measured when the child was born and at 14 years. RESULTS: After controlling for confounding factors, those who started using cannabis before age 15 years and used it frequently at 21 years were more likely to report symptoms of AD in early adulthood (odds ratio 3.4; 95% CI 1.9-6.1). This association was of similar magnitude for those who had only used cannabis and those who reported having used cannabis and other illicit drugs. CONCLUSION: The relationship between early-onset and frequent use of cannabis and symptoms of AD is independent of individual and family backgrounds. Frequent cannabis use is associated with increased AD in young adults independently of whether the person also uses other illicit drugs.