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|Title:||Nasopharyngeal pH monitoring in chronic sinusitis patients using a novel four channel probe|
|Citation:||The Laryngoscope, 2004; 114(9):1582-1586|
|Publisher:||Lippincott Williams & Wilkins|
|Abstract:||<h4>Objective</h4>To determine the prevalence of acid reflux into the nasopharynx in patients with chronic sinusitis.<h4>Study design</h4>Prospective study of patients presenting to a specialist rhinology practice with chronic sinusitis.<h4>Methods</h4>Forty patients with chronic sinusitis underwent ambulatory 24 hour pH testing. The mean age of the patients was 56.3 years (25 Female, 15 Male). The studies were performed using a specially developed bifurcated 4 channel pH probe, incorporating 2 circumferential sensors positioned at the naso- and hypo-pharynx, and 2 unidirectional sensors positioned at the proximal and distal esophagus.<h4>Results</h4>The circumferential band sensors yielded a stable recording largely free of artefact allowing meaningful recordings to be obtained from thirty-seven patients. Twelve patients (32.4%) were diagnosed with gastroesophageal reflux. A total of 809 reflux episodes were recorded. Of these, 596 (73.7%) reached the distal esophagus, with 187 (23.1%) and 24 (3.0%) reaching the proximal esophagus and hypopharynx respectively. Only 2 episodes (0.2%) were recorded in the nasopharynx. This occurred in 2 of 37 patients (5%).<h4>Conclusions</h4>Acid reflux into the nasopharynx is a rare event in patients with chronic sinusitis even though a significant proportion (32.4%) have abnormal 24 hour pH studies. It is likely that alternative mechanisms other than direct acid contact are involved in the pathogenesis of chronic sinusitis.|
Gastric Acidity Determination
Reproducibility of Results
Signal Processing, Computer-Assisted
|Description:||Copyright © 2004 The American Laryngological, Rhinological & Otological Society|
|Appears in Collections:||Aurora harvest 2|
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