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Type: Conference paper
Title: Extracting something from nothing: In vivo imaging of human cutaneous lymphatic vessels using optical coherence tomography
Author: Gong, P.
Es'Haghian, S.
Harms, K.
Murray, A.
Rea, S.
Wood, F.
Sampson, D.
McLaughlin, R.
Citation: Proceedings of the 29th IEEE Photonics Conference (IPC 2016), 2017, pp.138-139
Publisher: IEEE
Publisher Place: Online
Issue Date: 2017
Series/Report no.: IEEE Photonics Conference
ISBN: 1509019073
ISSN: 2374-0140
Conference Name: 29th IEEE Photonics Conference (IPC 2016) (2 Oct 2016 - 6 Oct 2016 : Waikoloa, HI)
Statement of
Peijun Gong, Shaghayegh Es'haghian, Karl-Anton Harms, Alexandra Murray, Suzanne Rea, Fiona M. Wood, David D. Sampson, and Robert A. McLaughlin
Abstract: We propose a method to image cutaneous lymphatic vessels in vivo with optical coherence tomography (OCT). Our method segments the transparent lymphatic vessels by thresholding the OCT signal after calibration for systematic variations due to the confocal effect and the sensitivity drop-off, and subsequent compensation for light attenuation with depth. We describe the method and present a pilot demonstration on two human burn scar patients undergoing ablative laser fractionation treatment. The results show visualization of the lymphatic vessels (diameter: ~30-150 μm) separate from the blood microvasculature network.
Rights: ©2016 IEEE
DOI: 10.1109/IPCon.2016.7831014
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