Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/11372
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Type: Journal article
Title: Defining the SOS operon of coliphage 186
Author: Brumby, A.
Lamont, I.
Dodd, I.
Egan, J.
Citation: Virology, 1996; 219(1):105-114
Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE
Issue Date: 1996
ISSN: 0042-6822
1096-0341
Abstract: We have sequenced the LexA-controlled operon of coliphage 186 that carries the tum gene, whose product is necessary for UV induction of the 186 prophage. The operon consists of orf95 and orf97, and we have identified orf95 as the tum gene. The major translation products from orf95 result from internal initiations and modulate Tum activity. Tum is the product of the full-length Orf95 protein. The second gene of the operon, orf97, is of unknown function but, while it has little effect on prophage induction, its presence in the cell totally blocks infection of that cell by 186.
Keywords: Escherichia coli; Coliphages; Viral Proteins; DNA, Viral; SOS Response (Genetics); Amino Acid Sequence; Base Sequence; Operon; Genes, Viral; Open Reading Frames; Molecular Sequence Data
Rights: Copyright © 1996 Academic Press. All rights reserved.
RMID: 0030004362
DOI: 10.1006/viro.1996.0227
Appears in Collections:Biochemistry publications

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