Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/118314
Citations
Scopus Web of Science® Altmetric
?
?
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAndraweera, P.en
dc.contributor.authorDekker, G.en
dc.contributor.authorLeemaqz, S.en
dc.contributor.authorMcCowan, L.en
dc.contributor.authorMyers, J.en
dc.contributor.authorKenny, L.en
dc.contributor.authorWalker, J.en
dc.contributor.authorPoston, L.en
dc.contributor.authorRoberts, C.T.en
dc.date.issued2019en
dc.identifier.citationObesity, 2019; 27(2):237-244en
dc.identifier.issn1930-7381en
dc.identifier.issn1930-739Xen
dc.identifier.urihttp://hdl.handle.net/2440/118314-
dc.description.abstractOBJECTIVE:This study investigated the influence of birth weight on the risk of pregnancy complications, including preeclampsia (PE), gestational hypertension (GH), small for gestational age (SGA) pregnancy, spontaneous preterm birth, and gestational diabetes mellitus (GDM), and assessed the effect of early pregnancy BMI on this relationship. METHODS:A total of 5,336 nulliparous women from the SCreening fOr Pregnancy Endpoints (SCOPE) study were included. Women's birth weights were self-reported and confirmed via medical records when possible. A birth weight of 3,000 to 3,499 g was considered the reference. RESULTS:After adjusting for confounders, birth weight < 2,500 g was associated with increased risk of GH (adjusted odds ratio [aOR] = 2.2, 95% CI = 1.3-3.7), PE (aOR = 1.7, 95% CI = 1.0-2.9), small for gestational age (aOR = 1.9, 95% CI = 1.1-3.2), and GDM (aOR = 2.4, 95% CI = 1.0-5.8) compared with the referent. Women born with birth weight < 2,500 g and who subsequently developed overweight or were diagnosed with obesity were at increased risk of GH (aOR = 2.2, 95% CI = 1.1-4.5), PE (aOR = 2.3, 95% CI = 1.2-4.5), and GDM (aOR = 3.2, 95% CI = 1.1-9.5) compared with women with birth weight ≥ 2,500 g and remained lean. CONCLUSIONS:Women who were born with a low birth weight are at increased risk of pregnancy complications. Those born small may have undergone "programming" in response to unfavorable intrauterine conditions. In such women, the physiological demands of pregnancy may act as a "second hit," leading to pregnancy complications.en
dc.description.statementofresponsibilityPrabha H. Andraweera, Gus Dekker, Shalem Leemaqz, Lesley McCowan, Jenny Myers, Louise Kenny, James Walker, Lucilla Poston, Claire T. Roberts on behalf of the SCOPE Consortiumen
dc.language.isoenen
dc.publisherWileyen
dc.rights© 2018 The Obesity Societyen
dc.subjectSCOPE Consortiumen
dc.titleEffect of birth weight and early pregnancy BMI on risk for pregnancy complicationsen
dc.typeJournal articleen
dc.identifier.rmid0030105923en
dc.identifier.doi10.1002/oby.22375en
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/GNT1090778en
dc.identifier.pubid453318-
pubs.library.collectionObstetrics and Gynaecology publicationsen
pubs.library.teamDS10en
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidAndraweera, P. [0000-0003-2434-8370]en
dc.identifier.orcidDekker, G. [0000-0002-7362-6683]en
dc.identifier.orcidLeemaqz, S. [0000-0003-4616-8426]en
dc.identifier.orcidRoberts, C.T. [0000-0002-9250-2192]en
Appears in Collections:Obstetrics and Gynaecology publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.