Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/11866
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DC Field | Value | Language |
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dc.contributor.author | Coates, A. | - |
dc.contributor.author | Noakes, M. | - |
dc.contributor.author | Clifton, P. | - |
dc.date.issued | 2001 | - |
dc.identifier.citation | Journal of Asthma, 2001; 38(4):311-319 | - |
dc.identifier.issn | 0277-0903 | - |
dc.identifier.issn | 1532-4303 | - |
dc.identifier.uri | http://hdl.handle.net/2440/11866 | - |
dc.description.abstract | We investigated in a clinical setting whether increased intake of linoleic acid alters respiratory function in 26 mild asthmatics. Subjects completed a 16-week-dietary intervention comprising 8 weeks eating an enriched n-6 polyunsaturated fat diet (9.2% energy from linoleic acid) and consuming either a high monounsaturated or saturated fat diet in a random cross-over resign for 8 weeks. Neither FEV1 nor PC20 values changed significantly after increased linoleic acid consumption when compared with the other diets. Increased consumption of linoleic acid caused a 20% rise (p < or = 0.01) in plasma linoleic acid, a 38% decrease (p < or = 0.01) in plasma eicosapentaenoic acid, but no change in arachidonic acid. There were no changes in symptom scores or bronchodilator use. | - |
dc.language.iso | en | - |
dc.publisher | Marcel Dekker Inc | - |
dc.source.uri | http://dx.doi.org/10.1081/jas-100002297 | - |
dc.subject | Humans | - |
dc.subject | Asthma | - |
dc.subject | Histamine | - |
dc.subject | Margarine | - |
dc.subject | Fatty Acids | - |
dc.subject | Linoleic Acid | - |
dc.subject | Peak Expiratory Flow Rate | - |
dc.subject | Forced Expiratory Volume | - |
dc.subject | Cross-Over Studies | - |
dc.subject | Middle Aged | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.title | The role of n-6 polyunsaturated fat in stable asthmatics | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1081/JAS-100002297 | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Clifton, P. [0000-0002-6411-626X] | - |
Appears in Collections: | Aurora harvest 7 Physiology publications |
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