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https://hdl.handle.net/2440/118712
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Type: | Journal article |
Title: | Aspirin use and early age-related macular degeneration: a meta-analysis |
Author: | Kahawita, S. Casson, R. |
Citation: | Canadian Journal of Ophthalmology, 2014; 49(1):35-39 |
Publisher: | Canadian Ophthalmological Society |
Issue Date: | 2014 |
ISSN: | 0008-4182 1715-3360 |
Statement of Responsibility: | Shyalle K.Kahawita, Robert J.Casson |
Abstract: | Objective: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). Methods: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). Results: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09–1.88). Conclusions: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation. |
Keywords: | Platelet Aggregation Inhibitors |
Rights: | Crown Copyright © 2014 Published by Elsevier Inc on behalf of the Canadian Ophthalmological Society. All rights reserved. |
DOI: | 10.1016/j.jcjo.2013.07.016 |
Published version: | http://dx.doi.org/10.1016/j.jcjo.2013.07.016 |
Appears in Collections: | Aurora harvest 4 Medicine publications |
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