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Type: Journal article
Title: Aspirin use and early age-related macular degeneration: a meta-analysis
Author: Kahawita, S.
Casson, R.
Citation: Canadian Journal of Ophthalmology, 2014; 49(1):35-39
Publisher: Canadian Ophthalmological Society
Issue Date: 2014
ISSN: 0008-4182
Statement of
Shyalle K.Kahawita, Robert J.Casson
Abstract: Objective: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). Methods: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). Results: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09–1.88). Conclusions: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation.
Keywords: Platelet Aggregation Inhibitors
Rights: Crown Copyright © 2014 Published by Elsevier Inc on behalf of the Canadian Ophthalmological Society. All rights reserved.
DOI: 10.1016/j.jcjo.2013.07.016
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