Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/124069
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Type: Journal article
Title: Magnetic resonance imaging in non-conditional pacemakers and implantable cardioverter-defibrillators: a systematic review and meta-analysis
Author: Munawar, D.A.
Chan, J.E.Z.
Emami, M.
Kadhim, K.
Khokhar, K.
O'shea, C.
Iwai, S.
Pitman, B.
Linz, D.
Munawar, M.
Roberts-Thomson, K.
Young, G.D.
Mahajan, R.
Sanders, P.
Lau, D.H.
Citation: Europace, 2020; 22(2):288-298
Publisher: Oxford University Press
Issue Date: 2020
ISSN: 1099-5129
1532-2092
Statement of
Responsibility: 
Dian A. Munawar, Joel E.Z. Chan, Mehrdad Emami, Kadhim Kadhim, Kashif Khokhar, Catherine O’Shea ... et al.
Abstract: AIMS: There is growing evidence that magnetic resonance imaging (MRI) scanning in patients with non-conditional cardiac implantable electronic devices (CIEDs) can be performed safely. Here, we aim to assess the safety of MRI in patients with non-conditional CIEDs. METHODS AND RESULTS: English scientific literature was searched using PubMed/Embase/CINAHL with keywords of 'magnetic resonance imaging', 'pacemaker', 'implantable defibrillator', and 'cardiac resynchronization therapy'. Studies assessing outcomes of adverse events or significant changes in CIED parameters after MRI scanning in patients with non-conditional CIEDs were included. References were excluded if the MRI conditionality of the CIEDs was undisclosed; number of patients enrolled was <10; or studies were case reports/series. About 35 cohort studies with a total of 5625 patients and 7196 MRI scans (0.5-3 T) in non-conditional CIEDs were included. The overall incidence of lead failure, electrical reset, arrhythmia, inappropriate pacing and symptoms related to pocket heating, or torque ranged between 0% and 1.43%. Increase in pacing lead threshold >0.5 V and impedance >50Ω was seen in 1.1% [95% confidence interval (CI) 0.7-1.8%] and 4.8% (95% CI 3.3-6.4%) respectively. The incidence of reduction in P- and R-wave sensing by >50% was 1.5% (95% CI 0.6-2.9%) and 0.4% (95% CI 0.06-1.1%), respectively. Battery voltage reduction of >0.04 V was reported in 2.2% (95% CI 0.2-6.1%). CONCLUSION: This meta-analysis affirms the safety of MR imaging in non-conditional CIEDs with no death or implantable cardioverter-defibrillator shocks and extremely low incidence of lead or device-related complications.
Keywords: Cardiac implantable electronic devices
Cardiac resynchronization therapy
Implantable cardioverter-defibrillators
Magnetic resonance imaging
Meta-analysis
Pacemakers
Rights: © The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/ 4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
DOI: 10.1093/europace/euz343
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