Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/127263
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Type: Journal article
Title: Gestational weight gain-re-examining the current paradigm
Author: Louise, J.
Deussen, A.R.
Dodd, J.M.
Citation: Nutrients, 2020; 12(8):1-12
Publisher: MDPI
Issue Date: 2020
ISSN: 2072-6643
2072-6643
Statement of
Responsibility: 
Jennie Louise, Andrea R. Deussen and Jodie M. Dodd
Abstract: Our aim was to investigate the underlying assumptions of the current gestational weight gain (GWG) paradigm, specifically that-(1) GWG is modifiable through diet and physical activity; (2) optimal GWG and risk of excess GWG, vary by pre-pregnancy body mass index (BMI) category and (3) the association between GWG and adverse pregnancy outcomes is causal. Using data from three large, harmonized randomized controlled trials (RCTs) of interventions to limit GWG and improve pregnancy outcomes and with appropriate regression models, we investigated the link between diet and physical activity and GWG; the relationships between pre-pregnancy BMI, GWG and birth weight z-score; and the evidence for a causal relationship between GWG and pregnancy outcomes. We found little evidence that diet and physical activity in pregnancy affected GWG and that the observed relationships between GWG and adverse pregnancy outcomes are causal in nature. Further, while there is evidence that optimal GWG may be lower for women with higher BMI, target ranges defined by BMI categories do not accurately reflect risk of adverse outcomes. Our findings cast doubt upon current advice regarding GWG, particularly for overweight and obese women and suggest that a change in focus is warranted.
Keywords: causal
gestational weight gain
obesity
pregnancy dietary and lifestyle intervention
Rights: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
DOI: 10.3390/nu12082314
Grant ID: http://purl.org/au-research/grants/nhmrc/1078980
http://purl.org/au-research/grants/nhmrc/519240
http://purl.org/au-research/grants/nhmrc/1043181
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