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https://hdl.handle.net/2440/127263
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Type: | Journal article |
Title: | Gestational weight gain-re-examining the current paradigm |
Author: | Louise, J. Deussen, A.R. Dodd, J.M. |
Citation: | Nutrients, 2020; 12(8):1-12 |
Publisher: | MDPI |
Issue Date: | 2020 |
ISSN: | 2072-6643 2072-6643 |
Statement of Responsibility: | Jennie Louise, Andrea R. Deussen and Jodie M. Dodd |
Abstract: | Our aim was to investigate the underlying assumptions of the current gestational weight gain (GWG) paradigm, specifically that-(1) GWG is modifiable through diet and physical activity; (2) optimal GWG and risk of excess GWG, vary by pre-pregnancy body mass index (BMI) category and (3) the association between GWG and adverse pregnancy outcomes is causal. Using data from three large, harmonized randomized controlled trials (RCTs) of interventions to limit GWG and improve pregnancy outcomes and with appropriate regression models, we investigated the link between diet and physical activity and GWG; the relationships between pre-pregnancy BMI, GWG and birth weight z-score; and the evidence for a causal relationship between GWG and pregnancy outcomes. We found little evidence that diet and physical activity in pregnancy affected GWG and that the observed relationships between GWG and adverse pregnancy outcomes are causal in nature. Further, while there is evidence that optimal GWG may be lower for women with higher BMI, target ranges defined by BMI categories do not accurately reflect risk of adverse outcomes. Our findings cast doubt upon current advice regarding GWG, particularly for overweight and obese women and suggest that a change in focus is warranted. |
Keywords: | causal gestational weight gain obesity pregnancy dietary and lifestyle intervention |
Rights: | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
DOI: | 10.3390/nu12082314 |
Grant ID: | http://purl.org/au-research/grants/nhmrc/1078980 http://purl.org/au-research/grants/nhmrc/519240 http://purl.org/au-research/grants/nhmrc/1043181 |
Published version: | http://dx.doi.org/10.3390/nu12082314 |
Appears in Collections: | Aurora harvest 8 Medicine publications |
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