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|Title:||The influence of DHA supplementation during pregnancy on language development across childhood: follow-up of a randomised controlled trial|
|Citation:||Prostaglandins, Leukotrienes and Essential Fatty Acids, 2020; 163:102207-1-102207-12|
|N.R. Gawlik, M. Makrides, L. Kettler, L.N. Yelland, S. Leemaqz, J.F. Gould|
|Abstract:||Numerous randomised controlled trials have explored the effect of docosahexaenoic acid (DHA) supplementation in early life on neurodevelopment, with some suggested positive effects on language. Australian women with a singleton pregnancy <21 weeks' gestation were randomised to receive 800 mg DHA/day or a placebo until birth. A sample of 726 children (all n=96 born preterm, random sample of n=630 born at term) were invited to undergo assessments of language, academic, and language-based cognitive abilities at 1.5, four and seven years of age. No group differences were detected for any group comparison. Exploratory analyses for sex by treatment interactions revealed a possible adverse effect of DHA supplementation on the language of females at 1.5 years but no effects on outcomes at four or seven years. Taken as a whole, evidence of an effect of prenatal DHA supplementation on language abilities across childhood is negligible and could be a chance finding.|
|Keywords:||DHA; omega-3 fatty acids; pregnancy; supplementation; language; verbal abilities|
|Rights:||© 2020 Elsevier Ltd. All rights reserved.|
|Appears in Collections:||Aurora harvest 8|
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