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Type: Journal article
Title: Atopic disease in childhood
Author: Gold, M.
Kemp, A.
Citation: Medical Journal of Australia, 2005; 182(6):298-304
Publisher: Australasian Med Publ Co Ltd
Issue Date: 2005
ISSN: 0025-729X
Statement of
Michael S Gold and Andrew S Kemp
Abstract: A child with atopy produces IgE antibodies after exposure to common environmental allergens. The atopic diseases (eczema, asthma and rhinoconjunctivitis) are clinical syndromes each defined by a group of symptoms and signs. Not all children with atopy will have atopic disease or develop symptoms after exposure to an allergen. Both genetic and environmental factors determine the development of atopic disease. The presence of specific IgE antibodies to environmental allergens is determined with skin prick or radioallergosorbent testing in children with atopy. Test results should be interpreted in the context of the clinical history and further investigations (eg, allergen avoidance or challenge). Management of atopic disease is frequently symptomatic, but it is important to avoid identified allergen triggers. Immunotherapy may be considered in selected school-age children with severe rhinoconjunctivitis. Preventing atopic disease in high-risk infants and hindering progression of disease in children with established disease are the areas of active research.
Keywords: Allergens
Conjunctivitis, Allergic
Environmental Exposure
Food Hypersensitivity
Genetic Predisposition to Disease
Risk Factors
Skin Tests
Description: The document attached has been archived with permission from the editor of the Medical Journal of Australia. An external link to the publisher’s copy is included.
DOI: 10.5694/j.1326-5377.2005.tb06707.x
Published version:
Appears in Collections:Aurora harvest 2
Paediatrics publications

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