Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/23339
Citations
Scopus Web of ScienceĀ® Altmetric
?
?
Type: Journal article
Title: Effect of mobile telephony on blood-brain barrier permeability in the fetal mouse brain
Author: Finnie, J.
Blumbergs, P.
Cai, Z.
Manavis, J.
Kuchel, T.
Citation: Pathology, 2006; 38(1):63-65
Publisher: Taylor & Francis
Issue Date: 2006
ISSN: 0031-3025
1465-3931
Abstract: <h4>Aims</h4>To study the effect of mobile telephone exposure on blood-brain barrier (BBB) permeability in the immature brain.<h4>Methods</h4>Using a purpose-designed exposure system at 900 MHz, pregnant mice were given a single, far-field, whole body exposure at a specific absorption rate of 4 W/kg for 60 min/day from day 1 to day 19 of gestation. Pregnant control mice were sham-exposed or freely mobile in a cage without further restraint and a positive control group with cadmium-induced BBB damage was also included. Immediately prior to parturition on gestational day 19, fetal heads were collected, fixed in Bouin's fixative and paraffin embedded. Disruption of BBB integrity was detected immunohistochemically using endogenous albumin as a vascular tracer in cerebral cortex, thalamus, basal ganglia, hippocampus, cerebellum, midbrain and medulla.<h4>Results</h4>No albumin extravasation was found in exposed or control brains.<h4>Conclusion</h4>In this animal model, whole of gestation exposure to global system for mobile communication-like radiofrequency fields did not produce any increase in vascular permeability in the fetal brain regions studied using endogenous albumin as a light microscopic immunohistochemical marker.
Keywords: Blood-Brain Barrier
Brain
Mesencephalon
Cerebellum
Hippocampus
Thalamus
Cerebral Cortex
Animals
Mice, Inbred BALB C
Mice
Prenatal Exposure Delayed Effects
Cadmium
Albumins
Immunohistochemistry
Models, Animal
Cell Membrane Permeability
Pregnancy
Radio Waves
Female
Cell Phone
DOI: 10.1080/00313020500459607
Appears in Collections:Aurora harvest 6
Medicine publications

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.