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https://hdl.handle.net/2440/38982
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dc.contributor.author | McMahon, C. | - |
dc.contributor.author | Stuckey, B. | - |
dc.contributor.author | Lording, D. | - |
dc.contributor.author | Wittert, G. | - |
dc.contributor.author | Murphy, A. | - |
dc.contributor.author | Shin, J. | - |
dc.contributor.author | Sutherland, P. | - |
dc.contributor.author | Palmer, N. | - |
dc.contributor.author | Lowy, M. | - |
dc.contributor.author | Jesudason, D. | - |
dc.contributor.author | Fredlund, P. | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | International Journal of Clinical Practice, 2005; 59(2):143-149 | - |
dc.identifier.issn | 1368-5031 | - |
dc.identifier.issn | 1742-1241 | - |
dc.identifier.uri | http://hdl.handle.net/2440/38982 | - |
dc.description | The definitive version is available at www.blackwell-synergy.com | - |
dc.description.abstract | The efficacy and safety of tadalafil for the treatment of erectile dysfunction (ED) were assessed in a 6-month, randomised, double-blind, placebo-controlled study. Australian men with mild, moderate or severe ED of organic, psychogenic or mixed aetiology were randomised to tadalafil 20 mg as needed (n = 93) or placebo (n = 47). Efficacy assessments included the international index of erectile function (IIEF) and the sexual encounter profile (SEP) diary. Tadalafil significantly improved erectile function compared with placebo (p < 0.001, all measures). At the end of the study, the mean per-patient proportion of successful sexual intercourse attempts (SEP question three) was 73.5% for patients treated with tadalafil and 26.8% for placebo-treated patients. Improved erections were reported by 78% of tadalafil-treated patients compared to 12.8% of placebo-treated patients. The most common treatment-emergent adverse events--headache and dyspepsia--were generally mild or moderate. Tadalafil was effective and well tolerated in Australian men with mild to severe ED. | - |
dc.description.statementofresponsibility | C.G. McMahon, B.G.A. Stuckey, D.W. Lording, G.A. Wittert, A. Murphy, J. Shin, P.D. Sutherland, N.R. Palmer, M.P. Lowy, D.R. Jesudason, P. Fredlund | - |
dc.language.iso | en | - |
dc.publisher | Medicom International | - |
dc.source.uri | http://dx.doi.org/10.1111/j.1742-1241.2005.00451.x | - |
dc.subject | Humans | - |
dc.subject | Carbolines | - |
dc.subject | Phosphodiesterase Inhibitors | - |
dc.subject | Treatment Outcome | - |
dc.subject | Double-Blind Method | - |
dc.subject | Adult | - |
dc.subject | Aged | - |
dc.subject | Middle Aged | - |
dc.subject | Australia | - |
dc.subject | Male | - |
dc.subject | Erectile Dysfunction | - |
dc.subject | Tadalafil | - |
dc.title | A 6-month study of the efficacy and safety of tadalafil in the treatment of erectile dysfunction: A randomised double-blind parallel-group placebo-controlled study in Australian men | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/j.1742-1241.2005.00451.x | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Wittert, G. [0000-0001-6818-6065] | - |
Appears in Collections: | Aurora harvest Medicine publications |
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