Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/41856
Type: | Patent |
Title: | Cleavage of BiP by Subtilase Cytotoxin |
Author: | Paton, A. Paton, J. Backer, M. Backer, J. |
Issue Date: | 2008 |
Assignee: | Adelaide Research & Innovation |
Organisation: | Adelaide Research & Innovation Pty Ltd |
Abstract: | Cleavage of BIP (Immunoglobulin binding protein) by subtilase toxin and its application to inhibiting growth of or killing of cells. This has application to treatment of cancers and to conformational diseases and in particular to conformational diseases involving BiP that are influenced by cleavage by the subtilase cytotoxin. The invention also relates to subtilase toxin molecules specifically targeting proliferating cells, in particular tumor cells, or cells expressing a vascular endothelial growth factor receptor. |
Patent #: | Int App No: PCT/AU2007/001111 |
Published version: | http://www.wipo.int/pctdb/en/wo.jsp?ELEMENT_SET=F&LANGUAGE=ENG&KEY=08/014574&IA=08/014574&DISPLAY=STATUS |
Appears in Collections: | Aurora harvest 6 Microbiology and Immunology publications |
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