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Type: Journal article
Title: Early investigation and treatment of obstructive sleep apnoea after acute stroke
Author: Broadley, S.
Jorgensen, L.
Cheek, A.
Salonikis, S.
Taylor, J.
Thompson, P.
Antic, R.
Citation: Journal of Clinical Neuroscience, 2007; 14(4):328-333
Publisher: Churchill Livingstone
Issue Date: 2007
ISSN: 0967-5868
Statement of
Simon A. Broadley, Lisbeth Jørgensen, Alison Cheek, Suzie Salonikis, Jamie Taylor, Philip D. Thompson and Ral Antic
Abstract: Obstructive sleep apnoea (OSA) is an independent risk factor for hypertension, which is a major cause of stroke. The prevalence and associations of OSA in a cohort of stroke patients were studied. The safety and tolerability of early treatment with nasal continuous airways pressure (nCPAP) was also assessed. Consecutive subjects admitted with acute stroke were assessed clinically, radiologically and with scales assessing prior OSA risk, dysphagia and disability. Sleep studies were performed within the first few days of admission using a portable diagnostic system. Twenty-nine of 55 (53%) subjects had evidence of OSA, using an apnoea-hypopnoea index (AHI) of 10 or greater. The AHI was significantly associated with an index of prior OSA symptoms, but not with history of hypertension, degree of dysphagia, or type and severity of stroke. Use of a portable diagnostic system for detecting OSA in the acute stroke setting was well tolerated. OSA is common after acute stroke and exceeds rates seen in control populations of similar age (53% vs. 11%). Early treatment with nCPAP was effective and well tolerated.
Keywords: Humans
Sleep Apnea, Obstructive
Acute Disease
Continuous Positive Airway Pressure
Severity of Illness Index
Cohort Studies
Prospective Studies
Aged, 80 and over
Middle Aged
Point-of-Care Systems
Description: Copyright © 2006 Elsevier Ltd All rights reserved.
DOI: 10.1016/j.jocn.2006.01.017
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