Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Journal article
Title: Polycystic ovary syndrome
Author: Norman, R.
Dewailly, D.
Legro, R.
Hickey, T.
Citation: The Lancet, 2007; 370(9588):685-697
Publisher: Lancet Ltd
Issue Date: 2007
ISSN: 0140-6736
Statement of
Robert J Norman, Didier Dewailly, Richard S Legro and Theresa E Hickey
Abstract: Polycystic ovary syndrome is a heterogeneous endocrine disorder that affects about one in 15 women worldwide. The major endocrine disruption is excessive androgen secretion or activity, and a large proportion of women also have abnormal insulin activity. Many body systems are affected in polycystic ovary syndrome, resulting in several health complications, including menstrual dysfunction, infertility, hirsutism, acne, obesity, and metabolic syndrome. Women with this disorder have an established increased risk of developing type 2 diabetes and a still debated increased risk of cardiovascular disease. The diagnostic traits of polycystic ovary syndrome are hyperandrogenism, chronic anovulation, and polycystic ovaries, after exclusion of other conditions that cause these same features. A conclusive definition of the disorder and the importance of the three diagnostic criteria relative to each other remain controversial. The cause of polycystic ovary syndrome is unknown, but studies suggest a strong genetic component that is affected by gestational environment, lifestyle factors, or both.
Keywords: Humans
Polycystic Ovary Syndrome
Infertility, Female
Insulin Resistance
Risk Factors
Description: Copyright © 2007 Elsevier Ltd All rights reserved.
DOI: 10.1016/S0140-6736(07)61345-2
Description (link):
Published version:
Appears in Collections:Aurora harvest 6
Obstetrics and Gynaecology publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.