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|Title:||Ancient DNA from the first European farmers in 7500-year-old Neolithic sites|
|Citation:||Science, 2005; 310(5750):1016-1018|
|Publisher:||Amer Assoc Advancement Science|
|Wolfgang Haak, Peter Forster, Barbara Bramanti, Shuichi Matsumura, Guido Brandt, Marc Tänzer, Richard Villems, Colin Renfrew, Detlef Gronenborn, Kurt Werner Alt, Joachim Burger|
|Abstract:||The ancestry of modern Europeans is a subject of debate among geneticists, archaeologists, and anthropologists. A crucial question is the extent to which Europeans are descended from the first European farmers in the Neolithic Age 7500 years ago or from Paleolithic hunter-gatherers who were present in Europe since 40,000 years ago. Here we present an analysis of ancient DNA from early European farmers. We successfully extracted and sequenced intact stretches of maternally inherited mitochondrial DNA (mtDNA) from 24 out of 57 Neolithic skeletons from various locations in Germany, Austria, and Hungary. We found that 25% of the Neolithic farmers had one characteristic mtDNA type and that this type formerly was widespread among Neolithic farmers in Central Europe. Europeans today have a 150-times lower frequency (0.2%) of this mtDNA type, revealing that these first Neolithic farmers did not have a strong genetic influence on modern European female lineages. Our finding lends weight to a proposed Paleolithic ancestry for modern Europeans.|
|Keywords:||Humans; DNA, Mitochondrial; Genetics, Population; Population Dynamics; Emigration and Immigration; Base Sequence; Gene Frequency; Genetic Drift; Haplotypes; Cultural Evolution; Agriculture; History, Ancient; Computer Simulation; Molecular Sequence Data; European Continental Ancestry Group; Europe; Austria; Hungary; Germany; Female; Male|
|Rights:||© 2005 American Association for the Advancement of Science. All Rights Reserved.|
|Appears in Collections:||Earth and Environmental Sciences publications|
Environment Institute publications
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