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https://hdl.handle.net/2440/52280
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Type: | Journal article |
Title: | Prevalence and determinants of delayed gastric emptying in hospitalised Type 2 diabetic patients |
Author: | Kojecky, V. Bernatek, J. Horowitz, M. Zemek, S. Bakala, L. Hep, A. |
Citation: | World Journal of Gastroenterology, 2008; 14(10):1564-1569 |
Publisher: | W J G Press |
Issue Date: | 2008 |
ISSN: | 1007-9327 2219-2840 |
Statement of Responsibility: | Vladimir Kojecky, Jaromir Bernatek, Michael Horowitz, Stanislav Zemek, Jiri Bakala, Ales Hep |
Abstract: | <h4>Aim</h4>To determine the prevalence of delayed gastric emptying (GE) in older patients with Type 2 diabetes mellitus.<h4>Methods</h4>One hundred and forty seven patients with Type 2 diabetes, of whom 140 had been hospitalised, mean age 62.3 +/- 8.0 years, HbA1c 9.1% +/- 1.9%, treated with either oral hypoglycemic drugs or insulin were studied. GE of a solid meal (scintigraphy), autonomic nerve function, upper gastrointestinal symptoms, acute and chronic glycemic control were evaluated. Gastric emptying results were compared to a control range of hospitalised patients who did not have diabetes.<h4>Results</h4>Gastric emptying was delayed (T50 > 85 min) in 17.7% patients. Mean gastric emptying was slower in females (T50 72.1 +/- 72.1 min vs 56.9 +/- 68.1 min, P = 0.02) and in those reporting nausea (112.3 +/- 67.3 vs 62.7 +/- 70.0 min, P < 0.01) and early satiety (114.0 +/- 135.2 vs 61.1 +/- 62.6 min, P = 0.02). There was no correlation between GE with age, body weight, duration of diabetes, neuropathy, current glycemia or the total score for upper gastrointestinal symptoms.<h4>Conclusion</h4>Prolonged GE occurs in about 20% of hospitalised elderly patients with Type 2 diabetes when compared to hospitalised patients who do not have diabetes. Female gender, nausea and early satiety are associated with higher probability of delayed GE. |
Keywords: | Humans Gastrointestinal Diseases Diabetes Mellitus, Type 2 Nausea Prevalence Regression Analysis Case-Control Studies Predictive Value of Tests Sex Factors Gastrointestinal Motility Gastric Emptying Aged Middle Aged Inpatients Female Male Feeding and Eating Disorders |
DOI: | 10.3748/wjg.14.1564 |
Published version: | http://dx.doi.org/10.3748/wjg.14.1564 |
Appears in Collections: | Aurora harvest 5 Medicine publications |
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