Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/52553
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Type: Journal article
Title: Drug-eluting stent treatment of a radiation-induced left internal mammary arterial graft stenosis
Author: Puri, R.
Dundon, B.
Worthley, M.
Worthley, S.
Brown, M.
Citation: Circulation Journal, 2008; 72(11):1904-1906
Publisher: Blackwell Science Asia
Issue Date: 2008
ISSN: 1346-9843
1347-4820
Statement of
Responsibility: 
Rishi Puri, Benjamin K. Dundon, Matthew I. Worthley, Stephen G. Worthley and Michael A. Brown
Abstract: A 62-year-old man underwent radiotherapy to the left upper chest for treatment of Pancoast syndrome on a background of previous coronary artery bypass grafting 12 years earlier. Within 1 year, he developed significant stenoses of both the left internal mammary artery (LIMA) graft and ostial left vertebral artery, presumably related to therapeutic radiation exposure. Initially diagnosed using computed tomography coronary angiography, the patient underwent percutaneous coronary intervention and insertion of a drug-eluting stent (DES) to the ostium of the LIMA graft via a left radial approach. He remains clinically well at 6-month follow-up. This is the first reported case in the literature of DES treatment of a radiation-induced vascular stenosis; however, the incidence of cardiovascular disease is elevated in such cases. In patients with a prior history of mantle radiation, consideration should be given to the routine assessment of internal mammary conduits prior to coronary artery bypass surgery.
Keywords: Drug-eluting stent
Left internal mammary artery (LIMA) graft
Mantle radiation
Stenosis
Description: Copyright © 2008 The Japanese Circulation Society
DOI: 10.1253/circj.CJ-07-0997
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