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Type: Journal article
Title: An unexpected ending: brain death following acute severe asthma
Author: Galluccio, S.
Rai, S.
Sharley, P.
Citation: Critical Care and Resuscitation, 2008; 10(3):235-238
Publisher: Australasian Academy of Critical Care Medicine
Issue Date: 2008
ISSN: 1441-2772
Statement of
Steven T Galluccio, Sumeet Rai and Peter Sharley
Abstract: A 56-year-old woman presented to our hospital with acute severe asthma. As a consequence of severe refractory airflow limitation, moderate hypercapnia ensued for several days. Unexpectedly, the patient died as a result of brain stem herniation, in the absence of hypoxaemia, arterial hypotension or an intracranial mass lesion. We discuss the mechanisms that may have precipitated severe intracranial hypertension resulting in brain death, and the possible methods to detect and avoid such a devastating consequence.
Keywords: Humans
Status Asthmaticus
Brain Edema
Intracranial Hypertension
Fatal Outcome
Middle Aged
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