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Type: Journal article
Title: Effects of substrate hydrophobicity/hydrophilicity on the height measurement of individual DNA molecules.
Author: Wang, H.
Zhou, X.
An, H.
Guo, Y.
Sun, J.
Zhang, Y.
Hu, J.
Citation: Chinese Physics Letters, 2007; 24(3):644-647
Publisher: Chinese Physical Soc
Issue Date: 2007
ISSN: 0256-307X
Statement of
Wang, Hua-Bin; Zhou, Xing-Fei; An, Hong-Jie; Guo, Yun-Chang; Sun, Jie-Lin; Zhang, Yi and Hu, Jun
Abstract: Effects of substrate hydrophobicity/hydrophilicity on height measurement of individual ds-DNA molecules are investigated with tapping mode atomic force microscopy (TMAFM) and vibrating mode scanning polarization force microscopy (VSPFM). The measured heights of ds-DNA on hydrophobic highly oriented pyrolytic graphite (HOPG) are remarkably less than those on hydrophilic bare mica and Ni²⁺ treated mica in both TMAFM and VSPFM. By analysing the results, we propose that the hydrophobicity/hydrophilicity of substrate can greatly influence the height measurement of DNA molecules.
RMID: 0020093797
DOI: 10.1088/0256-307X/24/3/016
Appears in Collections:Earth and Environmental Sciences publications

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