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|Title:||Effects of substrate hydrophobicity/hydrophilicity on the height measurement of individual DNA molecules.|
|Citation:||Chinese Physics Letters, 2007; 24(3):644-647|
|Publisher:||Chinese Physical Soc|
|Wang, Hua-Bin; Zhou, Xing-Fei; An, Hong-Jie; Guo, Yun-Chang; Sun, Jie-Lin; Zhang, Yi and Hu, Jun|
|Abstract:||Effects of substrate hydrophobicity/hydrophilicity on height measurement of individual ds-DNA molecules are investigated with tapping mode atomic force microscopy (TMAFM) and vibrating mode scanning polarization force microscopy (VSPFM). The measured heights of ds-DNA on hydrophobic highly oriented pyrolytic graphite (HOPG) are remarkably less than those on hydrophilic bare mica and Ni²⁺ treated mica in both TMAFM and VSPFM. By analysing the results, we propose that the hydrophobicity/hydrophilicity of substrate can greatly influence the height measurement of DNA molecules.|
|Appears in Collections:||Earth and Environmental Sciences publications|
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