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Type: Journal article
Title: Resistance of degraded hair shafts to contaminant DNA
Author: Gilbert, M.
Menez, L.
Janaway, R.
Tobin, D.
Cooper, A.
Wilson, A.
Citation: Forensic Science International, 2006; 156(2):208-212
Publisher: Elsevier Sci Ireland Ltd
Issue Date: 2006
ISSN: 0379-0738
Statement of
M Thomas P Gilbert, Laura Menez, Robert C Janaway, Desmond J Tobin, Alan Cooper and Andrew S Wilson
Abstract: We have investigated the susceptibility of degraded human hair shaft samples to contamination by exogenous sources of DNA, including blood, saliva, skin cells, and purified DNA. The results indicate that on the whole hair shafts are either largely resistant to penetration by contaminant DNA, or extremely easy to successfully decontaminate. This pertains to samples that are both morphologically and biochemically degraded. We suggest that this resistance to the incorporation of contaminant DNA relates to the hydrophobic and impermeable nature of the keratin structures forming the hair shaft. Therefore, hair samples represent an important and underestimated source of DNA in both forensic and ancient DNA studies.
Keywords: Contamination; Degradation; Hair; mtDNA
RMID: 0020095861
DOI: 10.1016/j.forsciint.2005.02.021
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Appears in Collections:Earth and Environmental Sciences publications
Environment Institute Leaders publications

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