Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/57699
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Platypus chain reaction: directional and ordered meiotic pairing of the multiple sex chromosome chain in Ornithorhynchus anatinus |
Author: | Daish, T. Casey, A. Grutzner, F. |
Citation: | Reproduction Fertility and Development, 2009; 21(8):976-984 |
Publisher: | C S I R O Publishing |
Issue Date: | 2009 |
ISSN: | 1031-3613 1448-5990 |
Statement of Responsibility: | Tasman Daish, Aaron Casey and Frank Grützner |
Abstract: | Monotremes are phylogenetically and phenotypically unique animals with an unusually complex sex chromosome system that is composed of ten chromosomes in platypus and nine in echidna. These chromosomes are alternately linked (X1Y1, X2Y2, ...) at meiosis via pseudoautosomal regions and segregate to form spermatozoa containing either X or Y chromosomes. The physical and epigenetic mechanisms involved in pairing and assembly of the complex sex chromosome chain in early meiotic prophase I are completely unknown. We have analysed the pairing dynamics of specific sex chromosome pseudoautosomal regions in platypus spermatocytes during prophase of meiosis I. Our data show a highly coordinated pairing process that begins at the terminal Y5 chromosome and completes with the union of sex chromosomes X1Y1. The consistency of this ordered assembly of the chain is remarkable and raises questions about the mechanisms and factors that regulate the differential pairing of sex chromosomes and how this relates to potential meiotic silencing mechanisms and alternate segregation. |
Keywords: | chromosome pairing meiosis pseudoautosomal regions telomeres. |
Description: | © CSIRO 2009 |
DOI: | 10.1071/RD09085 |
Grant ID: | http://purl.org/au-research/grants/arc/DP0664267 http://purl.org/au-research/grants/arc/DP0664267 |
Published version: | http://dx.doi.org/10.1071/rd09085 |
Appears in Collections: | Aurora harvest Environment Institute Leaders publications Genetics publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.