Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/61225
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | microRNAs and EMT in mammary cells and breast cancer |
Author: | Wright, J. Richer, J. Goodall, G. |
Citation: | Journal of Mammary Gland Biology and Neoplasia, 2010; 15(2):213-223 |
Publisher: | Kluwer Academic/plenum Publ |
Issue Date: | 2010 |
ISSN: | 1083-3021 1573-7039 |
Statement of Responsibility: | Josephine A. Wright, Jennifer K. Richer and Gregory J. Goodall |
Abstract: | MicroRNAs are master regulators of gene expression in many biological and pathological processes, including mammary gland development and breast cancer. The differentiation program termed the epithelial to mesenchymal transition (EMT) involves changes in a number of microRNAs. Some of these microRNAs have been shown to control cellular plasticity through the suppression of EMT-inducers or to influence cellular phenotype through the suppression of genes involved in defining the epithelial and mesenchymal cell states. This has led to the suggestion that microRNAs maybe a novel therapeutic target for the treatment of breast cancer. In this review, we will discuss microRNAs that are involved in EMT in mammary cells and breast cancer. |
Keywords: | microRNA epithelial to mesenchymal transition mammary cells breast cancer |
Rights: | © Springer. Springer Science+Business Media |
DOI: | 10.1007/s10911-010-9183-z |
Published version: | http://dx.doi.org/10.1007/s10911-010-9183-z |
Appears in Collections: | Aurora harvest 5 Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.