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Type: Conference paper
Title: Impact of movement on cardiorespiratory coordination in conscious rats
Author: Kabir, M.
Nalivaiko, E.
Abbott, D.
Baumert, M.
Citation: Proceedings of the 32nd IEEE Engineering in Medicine and Biology Society (EMBS) Annual Conference 2010: pp.1938-1941
Publisher: IEEE
Publisher Place: CD
Issue Date: 2010
Series/Report no.: IEEE Engineering in Medicine and Biology Society Conference Proceedings
ISBN: 9781424441242
ISSN: 1557-170X
Conference Name: IEEE Engineering in Medicine and Biology Society. Conference (32nd : 2010 : Buenos Aires, Argentina)
Statement of
Muammar M. Kabir, Eugene Nalivaiko, Derek Abbott, and Mathias Baumert
Abstract: In this study we assessed the impact of movement on the interaction between the heart rhythm and respiration in rats while they were conscious and freely moving. In eight male adult Sprague-Dawley (SD, n=4) and Hooded Wistar (HW, n=4) rats, we recorded respiratory rate using whole-body plethysmography with a piezoelectric sensor attached to simultaneously monitor body movement. Heart rate was recorded using a radio-telemetry transmitter. For the assessment of cardiorespiratory coordination, we analysed the phase-locking between heart rate and respiration, estimating the instantaneous phases using Hilbert transform. For statistical analysis, the piezoelectric signal was dichotomized into lowintensity (LIm) and high-intensity (HIm) movement. The R-R intervals, respiratory intervals and cardiorespiratory coordination between LIm and HIm of each rat were assessed with Student’s t-test. A significant decrease in the mean values for respiratory interval (0.34±0.1 vs. 0.23±0.1 s, p<0.01 in HW rats) and R-R interval (0.19±0.01 vs. 0.17±0.01 s, p<0.001 in SD rats) was observed during HIm. The phase-locking between the cardiac and respiratory signals also decreased significantly during HIm (overall coordination during LIm vs. HIm: 89.3±3.3% vs. 8.7±1.7%, p<0.001). In conclusion the interaction between the cardiac and respiratory oscillators is affected by voluntary movements in rats.
Keywords: Animals
Rats, Wistar
Cardiovascular System
Data Interpretation, Statistical
Heart Rate
Rats, Sprague-Dawley
Rights: © 2010 IEEE
DOI: 10.1109/IEMBS.2010.5627748
Appears in Collections:Aurora harvest 5
Electrical and Electronic Engineering publications

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