Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/63804
Type: | Journal article |
Title: | The use of GLP-2 and related growth factors in intestinal diseases |
Author: | Yazbek, R. Abbott, C. Howarth, G. |
Citation: | Current Opinion in Investigational Drugs, 2010; 11(4):440-446 |
Publisher: | Current Drugs Ltd. |
Issue Date: | 2010 |
ISSN: | 1472-4472 2040-3429 |
Statement of Responsibility: | R. Yazbeck, C. A. Abbott, G. S. Howarth |
Abstract: | The pharmacological application of intestinal growth factors has been recognized because of the protective and reparative actions of these factors in the intestinal tract. This review highlights the use of keratinocyte growth factor (KGF), IGF-1 and glucagon-like peptide 2 (GLP-2) in efficacy studies of intestinal damage; the results from these studies support potential clinical applications of these factors in treating intestinal diseases. In particular, GLP-2 has been assessed in preclinical and clinical investigations for its capacity to prevent or treat an increasing number of intestinal diseases, including short bowel syndrome, chemotherapy-induced intestinal mucositis and inflammatory bowel disease. |
Keywords: | Animals Humans Mice Rats Intestinal Diseases Insulin-Like Growth Factor I Fibroblast Growth Factor 7 Glucagon-Like Peptide 2 |
Rights: | Copyright status unknown |
Description (link): | http://www.ncbi.nlm.nih.gov/pubmed/20336592 |
Appears in Collections: | Agriculture, Food and Wine publications Aurora harvest 5 |
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