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|Title:||Measurement of upper esophageal sphincter tone and relaxation during swallowing in premature infants|
|Citation:||American Journal of Physiology - Gastrointestinal and Liver Physiology, 1999; 277(4):G862-G866|
|Publisher:||AMER PHYSIOLOGICAL SOC|
|T. Omari, A. Snel, C. Barnett, G. Davidson, R. Haslam, and J. Dent|
|Abstract:||Upper esophageal sphincter (UES) motor function has not been previously evaluated in premature infants. The motor patterns associated with tonic activity and swallow-related relaxation of the UES were recorded for 1 h after completion of gavage feeding in 11 healthy preterm neonates (postmenstrual age 33-37 wk) with a micromanometric assembly, which included a sleeve sensor specifically adapted for UES recordings. A clearly defined UES high-pressure zone was observed in all premature infants studied. Resting UES pressure ranged from 2.3 to 26.2 mmHg and was higher during periods of irritability and apparent discomfort. During dry swallows, UES pressure relaxed from a resting pressure of 28.2 +/- 4.0 mmHg to a nadir of 1.1 +/- 3.3 mmHg. The mean UES relaxation interval (the time from relaxation onset to relaxation offset) was 0. 31 +/- 0.11 s. We conclude that in premature infants >/=33 wk postmenstrual age the motor mechanisms regulating UES resting pressure and the onset of UES relaxation are well developed.|
|Keywords:||esophageal motility; preterm infant|
|Rights:||Copyright © 1999 the American Physiological Society|
|Appears in Collections:||Paediatrics publications|
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