Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/70123
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Type: Journal article
Title: Prostaglandin F2α and control of reproduction in female swine: A review
Other Titles: Prostaglandin F2alpha and control of reproduction in female swine: A review
Author: De Rensis, F.
Saleri, R.
Tummaruk, P.
Techakumphu, M.
Kirkwood, R.
Citation: Theriogenology, 2012; 77(1):1-11
Publisher: Elsevier Science Inc
Issue Date: 2012
ISSN: 0093-691X
1879-3231
Statement of
Responsibility: 
F. De Rensis, R. Saleri, P. Tummaruk, M. Techakumphu, R.N. Kirkwood
Abstract: In female swine, PGF2α is an important regulator of corpora luteal (CL) function, uterine contractility, ovulation, and embryo attachment. High affinity PGF2α receptors are present in the CL at all stages of the estrous cycle and they are functional. Therefore, a lack of luteolytic capacity of PGF2α is related to other factors that have not been well identified. In female pigs, a single exogenous PGF2α injection produces a short lasting decrease in plasma progesterone levels but does not induce luteolysis before day 12 of the estrous cycle. However, multiple injections of PGF2α can induce luteolysis before day 12 of the estrous cycle and may be utilized in the development of protocols for ovulation synchronization and timed AI. Most commonly, PGF2α is used for the induction of farrowing and so facilitation of cross fostering. Further, since PGF2α is a smooth muscle stimulant, treatment to stimulate myometrial contractions and uterine evacuation of residual products from parturition or infectious debris, may have beneficial effects on post-weaning fertility. Administration of PGF2α at the moment of insemination has been shown to improve reproductive performances when fertility is otherwise low, such as in sow under summer heat stress.
Keywords: Corpus Luteum; Animals; Swine; Dinoprost; Receptors, Prostaglandin; Insemination, Artificial; Reproduction; Estrous Cycle; Luteolysis; Postpartum Period; Pregnancy; Female
Rights: Copyright © 2012 Elsevier Inc.
RMID: 0020115358
DOI: 10.1016/j.theriogenology.2011.07.035
Appears in Collections:Animal and Veterinary Sciences publications

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