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Type: Journal article
Title: The human OTF1 locus which overlaps the CD3Z gene is located at 1q22>q23
Author: Sturm, R.
Eyre, H.
Baker, E.
Sutherland, G.
Citation: Cytogenetics and Cell Genetics, 1995; 68(3-4):231-232
Publisher: S. Karger
Issue Date: 1995
ISSN: 0301-0171
Abstract: The human OTF1 locus encoding the Oct-1 protein has previously been mapped to chromosome 1 cen-->q32 by analysis of somatic cell hybrids. We report here the regional localization of OTF1 to 1q22-->q23 by fluorescence in situ hybridization. The physical linkage of the CD3Z gene to the OTF1 transcription unit also refines the location of the CD3Z locus to 1q22-->q23.
Keywords: Chromosomes, Human, Pair 1; Humans; DNA-Binding Proteins; Transcription Factors; DNA Probes; In Situ Hybridization, Fluorescence; Chromosome Mapping; Octamer Transcription Factor-1; Host Cell Factor C1; Genetic Linkage
RMID: 0030005675
DOI: 10.1159/000133919
Appears in Collections:Paediatrics publications

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