Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/72748
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Type: Journal article
Title: Diabetes risk score in the diagnostic categories of polycystic ovary syndrome
Author: Moran, L.
Strauss, B.
Teede, H.
Citation: Fertility and Sterility, 2011; 95(5):1742-1748
Publisher: Elsevier Science Inc
Issue Date: 2011
ISSN: 0015-0282
1556-5653
Statement of
Responsibility: 
Lisa J. Moran, Boyd J. Strauss and Helena J. Teede
Abstract: <h4>Objective</h4>To assess the Finnish Diabetes Risk Score in polycystic ovary syndrome (PCOS) and in different phenotypes of PCOS and controls.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>General community.<h4>Patient(s)</h4>Overweight premenopausal women with National Institutes of Health (NIH) PCOS (n = 29), non-NIH PCOS (n = 25), or controls (n = 27).<h4>Intervention(s)</h4>No intervention provided.<h4>Main outcome measure(s)</h4>Finnish Diabetes Risk Score, anthropometrics, oral glucose tolerance test (OGTT), glucose, insulin, and reproductive hormone levels.<h4>Result(s)</h4>The women with NIH PCOS had higher adiposity, abdominal adiposity and 120-minute OGTT glucose. The women with NIH and non-NIH PCOS had elevated 120-minute OGTT insulin compared with controls. The women with NIH (11.3 ± 0.7) and non-NIH PCOS (10.4 ± 0.7) had similar diabetes risk scores, but both had higher diabetes risk score compared with controls (7.6 ± 0.8) maintained on adjustment for age and body mass index (BMI). The women with NIH (4%) and non-NIH PCOS (12%) had a lower prevalence of low risk of diabetes scores compared with controls (50%).<h4>Conclusion(s)</h4>We report for the first time that women with NIH and non-NIH PCOS have similar Finnish Diabetes Risk Scores and elevated scores relative to controls independent of age and adiposity. Similar clinical screening and treatment practices for type 2 diabetes are warranted for both phenotypes of PCOS.
Keywords: Humans
Polycystic Ovary Syndrome
Diabetes Mellitus, Type 2
Diagnostic Techniques, Endocrine
Risk Factors
Case-Control Studies
Cross-Sectional Studies
Algorithms
Research Design
Adolescent
Adult
Middle Aged
Finland
Female
Young Adult
Rights: Copyright © 2011 American Society for Reproductive Medicine, Published by Elsevier Inc.
DOI: 10.1016/j.fertnstert.2011.01.133
Appears in Collections:Aurora harvest 5
Obstetrics and Gynaecology publications

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