Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||Diabetes risk score in the diagnostic categories of polycystic ovary syndrome|
|Citation:||Fertility and Sterility, 2011; 95(5):1742-1748|
|Publisher:||Elsevier Science Inc|
|Lisa J. Moran, Boyd J. Strauss and Helena J. Teede|
|Abstract:||OBJECTIVE: To assess the Finnish Diabetes Risk Score in polycystic ovary syndrome (PCOS) and in different phenotypes of PCOS and controls. DESIGN: Cross-sectional study. SETTING: General community. PATIENT(S): Overweight premenopausal women with National Institutes of Health (NIH) PCOS (n = 29), non-NIH PCOS (n = 25), or controls (n = 27). INTERVENTION(S): No intervention provided. MAIN OUTCOME MEASURE(S): Finnish Diabetes Risk Score, anthropometrics, oral glucose tolerance test (OGTT), glucose, insulin, and reproductive hormone levels. RESULT(S): The women with NIH PCOS had higher adiposity, abdominal adiposity and 120-minute OGTT glucose. The women with NIH and non-NIH PCOS had elevated 120-minute OGTT insulin compared with controls. The women with NIH (11.3 ± 0.7) and non-NIH PCOS (10.4 ± 0.7) had similar diabetes risk scores, but both had higher diabetes risk score compared with controls (7.6 ± 0.8) maintained on adjustment for age and body mass index (BMI). The women with NIH (4%) and non-NIH PCOS (12%) had a lower prevalence of low risk of diabetes scores compared with controls (50%). CONCLUSION(S): We report for the first time that women with NIH and non-NIH PCOS have similar Finnish Diabetes Risk Scores and elevated scores relative to controls independent of age and adiposity. Similar clinical screening and treatment practices for type 2 diabetes are warranted for both phenotypes of PCOS.|
|Keywords:||Humans; Polycystic Ovary Syndrome; Diabetes Mellitus, Type 2; Diagnostic Techniques, Endocrine; Risk Factors; Case-Control Studies; Cross-Sectional Studies; Algorithms; Research Design; Adolescent; Adult; Middle Aged; Finland; Female; Young Adult|
|Rights:||Copyright © 2011 American Society for Reproductive Medicine, Published by Elsevier Inc.|
|Appears in Collections:||Obstetrics and Gynaecology publications|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.