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Type: Journal article
Title: Molecular Characterization of a Nonneuronal Human Unc18 Homolog
Author: Ziegler, S.
Mortrud, M.
Swartz, A.
Baker, E.
Sutherland, G.
Burmeister, M.
Mulligan, J.
Citation: Genomics, 1996; 37(1):19-23
Issue Date: 1996
ISSN: 0888-7543
Abstract: A cDNA clone encoding a human homolog of the Caenorhabditis elegans unc-18 gene was identified following random sequencing of clones from IL-2-activated human NK cells. This cDNA clone is related to the nonneuronal Munc-18b and so has been called Hunc-18b. The Hunc-18b transcripts were found in most human tissues, with the exception of brain and skeletal muscle, and in cells from all lymphoid lineages. The Hunc-18b gene was localized to human chromosome 19p13.2-p13.3, and the mouse homolog, Munc-18b, was mapped to the proximal region of mouse Chromosome 8.
Keywords: Chromosomes, Human, Pair 19
Vesicular Transport Proteins
Nerve Tissue Proteins
DNA, Complementary
In Situ Hybridization, Fluorescence
Chromosome Mapping
Cloning, Molecular
Amino Acid Sequence
Sequence Homology, Amino Acid
Molecular Sequence Data
Munc18 Proteins
DOI: 10.1006/geno.1996.0515
Appears in Collections:Aurora harvest 5
Paediatrics publications

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