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|Scopus||Web of Science®|
|Title:||New cylindrical peptide assemblies defined by extended parallel β-sheets|
|Other Titles:||New cylindrical peptide assemblies defined by extended parallel beta-sheets|
|Citation:||Organic & Biomolecular Chemistry, 2013; 11(3):425-429|
|Publisher:||Royal Soc Chemistry|
|Ashok D. Pehere, Christopher J. Sumby and Andrew D. Abell|
|Abstract:||A new approach to non-covalent peptide-based nanotubular or rod-like structures is presented, whereby the monomeric units are preorganised into a β-strand geometry that templates the formation of an extended and unusual parallel β-sheet rod-like structure. The conformational constraint is introduced by Huisgen cycloaddition to give a triazole-based macrocycle, with the resulting self-assembled structures stabilized by a well-defined series of intermolecular hydrogen bonds.|
|Keywords:||Oligopeptides; Protein Structure, Secondary; Models, Molecular|
|Description:||Received 17 Aug 2012, Accepted 25 Sep 2012, First published on the web 26 Sep 2012 (from RCS website)|
|Rights:||© The Royal Society of Chemistry|
|Appears in Collections:||Chemistry publications|
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