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https://hdl.handle.net/2440/73562
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Type: | Journal article |
Title: | Immunogenicity and safety of measles-mumps-rubella and varicella vaccines coadministered with a fourth dose of Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine in toddlers: a pooled analysis of randomized trials |
Author: | Bryant, K. McVernon, J. Marchant, C. Nolan, T. Marshall, G. Richmond, P. Marshall, H. Nissen, M. Lambert, S. Aris, E. Mesaros, N. Miller, J. |
Citation: | Human Vaccines and Immunotherapeutics, 2012; 8(8):1036-1041 |
Publisher: | Landes Bioscience |
Issue Date: | 2012 |
ISSN: | 2164-554X 2164-554X |
Statement of Responsibility: | Kristina A. Bryant, Jodie McVernon, Colin D. Marchant, Terry Nolan, Gary S. Marshall, Peter Richmond, Helen Marshall, Michael Nissen, Stephen B. Lambert, Emmanuel Aris, Narcisa Mesaros and Jacqueline M. Miller |
Abstract: | A pooled analysis was conducted of 1,257 toddlers who received a fourth dose of Haemophilus influenzae type b-Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine (HibMenCY-TT ) or Hib conjugate vaccine (Hib polysaccharide conjugated to N. meningitidis outer membrane protein) coadministered with measles-mumps-rubella (MMR) and varicella (VAR) vaccines (NCT00134719/NCT00289783). Noninferiority of immunological responses to MMR and VAR was demonstrated between groups and incidences of MMR- and VAR-specific solicited symptoms were similar, indicating that HibMenCY-TT can be coadministered with MMR and VAR. |
Keywords: | Haemophilus influenzae tybe b Neisseria meningitidis scrogroups C and Y MMR varicella vaccination toddlers |
Rights: | © 2012 Landes Bioscience |
DOI: | 10.4161/hv.20357 |
Published version: | http://dx.doi.org/10.4161/hv.20357 |
Appears in Collections: | Aurora harvest Paediatrics publications |
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