Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/74720
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DC Field | Value | Language |
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dc.contributor.author | Moran, L. | - |
dc.contributor.author | Noakes, M. | - |
dc.contributor.author | Wittert, G. | - |
dc.contributor.author | Clifton, P. | - |
dc.contributor.author | Norman, R. | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Reproductive Biomedicine Online, 2012; 25(5):500-503 | - |
dc.identifier.issn | 1472-6483 | - |
dc.identifier.issn | 1472-6491 | - |
dc.identifier.uri | http://hdl.handle.net/2440/74720 | - |
dc.description.abstract | Polycystic ovary syndrome (PCOS) is associated with increased cardiovascular disease risk. The effect of weight loss on the vascular inflammatory markers plasminogen activator inhibitor-1 (PAI-1), asymmetric dimethylarginine (ADMA), soluble vascular cell adhesion molecule-1 (sVCAM-1) and intracellular adhesion molecule-1 (sICAM-1) is unknown. Overweight women with (n=14) and without (n=13) PCOS of comparable age and body mass index undertook an 8-week weight-loss programme. Women with PCOS had elevated PAI-1, sVCAM-1 and sICAM-1 before and after weight loss compared with the controls. For all women, sVCAM-1 (P=0.026) and sICAM-1 (P=0.04) decreased with weight loss. Women with PCOS have elevated inflammatory markers, which are partially reduced by weight loss. | - |
dc.description.statementofresponsibility | Lisa J Moran, Manny Noakes, Gary A Wittert, Peter M Clifton, Robert J Norman | - |
dc.language.iso | en | - |
dc.publisher | Reproductive Healthcare Ltd. | - |
dc.rights | Copyright © 2012 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved. | - |
dc.source.uri | http://dx.doi.org/10.1016/j.rbmo.2012.07.013 | - |
dc.subject | cardiovascular disease | - |
dc.subject | inflammation | - |
dc.subject | polycystic ovary syndrome | - |
dc.subject | weight loss | - |
dc.title | Weight loss and vascular inflammatory markers in overweight women with and without polycystic ovary syndrome | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1016/j.rbmo.2012.07.013 | - |
dc.relation.grant | NHMRC | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Moran, L. [0000-0001-5772-6484] | - |
dc.identifier.orcid | Wittert, G. [0000-0001-6818-6065] | - |
dc.identifier.orcid | Clifton, P. [0000-0002-6411-626X] | - |
dc.identifier.orcid | Norman, R. [0000-0002-3118-3896] | - |
Appears in Collections: | Aurora harvest Obstetrics and Gynaecology publications |
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