Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/76334
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dc.contributor.authorPrice, T.en
dc.date.issued2012en
dc.identifier.citationAnnals of Oncology, 2012; 23(10):2479-2516en
dc.identifier.issn0923-7534en
dc.identifier.issn1569-8041en
dc.identifier.urihttp://hdl.handle.net/2440/76334-
dc.description.abstractColorectal cancer (CRC) is the most common tumour type in both sexes combined in Western countries. Although screening programmes including the implementation of faecal occult blood test and colonoscopy might be able to reduce mortality by removing precursor lesions and by making diagnosis at an earlier stage, the burden of disease and mortality is still high. Improvement of diagnostic and treatment options increased staging accuracy, functional outcome for early stages as well as survival. Although high quality surgery is still the mainstay of curative treatment, the management of CRC must be a multi-modal approach performed by an experienced multi-disciplinary expert team. Optimal choice of the individual treatment modality according to disease localization and extent, tumour biology and patient factors is able to maintain quality of life, enables long-term survival and even cure in selected patients by a combination of chemotherapy and surgery. Treatment decisions must be based on the available evidence, which has been the basis for this consensus conference-based guideline delivering a clear proposal for diagnostic and treatment measures in each stage of rectal and colon cancer and the individual clinical situations. This ESMO guideline is recommended to be used as the basis for treatment and management decisions.en
dc.description.statementofresponsibilityH.J. Schmoll... T.J. Price... et al.en
dc.language.isoenen
dc.publisherOxford Univ Pressen
dc.rights© The Author 2012. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved.en
dc.subjectHumans; Colorectal Neoplasms; Prognosis; Decision Making; Counseling; Patient Care Team; Precision Medicineen
dc.titleESMO consensus guidelines for management of patients with colon and rectal cancer: a personalized approach to clinical decision makingen
dc.typeJournal articleen
dc.identifier.rmid0020125495en
dc.identifier.doi10.1093/annonc/mds236en
dc.identifier.pubid21271-
pubs.library.collectionMedicine publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidPrice, T. [0000-0002-3922-2693]en
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