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https://hdl.handle.net/2440/7774
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dc.contributor.author | Edwards, J. | - |
dc.contributor.author | Williams, J. | - |
dc.contributor.author | Thomas, D. | - |
dc.date.issued | 2004 | - |
dc.identifier.citation | Pathology, 2004; 36(4):330-334 | - |
dc.identifier.issn | 0031-3025 | - |
dc.identifier.issn | 1465-3931 | - |
dc.identifier.uri | http://hdl.handle.net/2440/7774 | - |
dc.description.abstract | <h4>Aim</h4>To provide a colorectal cancer screening service for the general public, based on the detection of blood in faeces, that was effective, affordable and convenient.<h4>Methods</h4>Kits for collecting faecal specimens were sold directly to the public and, after collecting three specimens, kits were transported to the laboratory for testing by an immunochemical procedure involving a positive cut-off value. Reports were sent to participants and their nominated doctors who were requested to provide information on participants testing positive.<h4>Results</h4>Over a 10-year period, 35 139 kits were analysed and 5.63% were positive. After follow-up, 7.4% of positive testing participants were found to have colorectal cancer, 23.4% adenomas, 34.6% miscellaneous non-neoplastic pathology and in 25.0% no abnormality was found. Sixty-six per cent of cancers were early stage, Dukes stages A and B. There were 35 139 kits processed on 16 240 individuals, indicating that a number were repeat testing.<h4>Conclusions</h4>The screening service was able to detect a high yield of colorectal pathology, especially early stage neoplasia which is curable, and encouraged repeat testing. Education of doctors about how to investigate a positive test, and of participants about symptoms, have been important lessons arising from this screening service. | - |
dc.description.statementofresponsibility | Edwards, John E ; Williams, J Anthony R ; Thomas, David W | - |
dc.language.iso | en | - |
dc.publisher | Taylor & Francis | - |
dc.source.uri | http://dx.doi.org/10.1080/00313020410001721519 | - |
dc.subject | Humans | - |
dc.subject | Colorectal Neoplasms | - |
dc.subject | Reagent Kits, Diagnostic | - |
dc.subject | Mass Screening | - |
dc.subject | Occult Blood | - |
dc.subject | Immunohistochemistry | - |
dc.subject | Sensitivity and Specificity | - |
dc.subject | Aged | - |
dc.subject | Aged, 80 and over | - |
dc.subject | Middle Aged | - |
dc.subject | Laboratories, Hospital | - |
dc.subject | Female | - |
dc.subject | Male | - |
dc.title | Experiences in providing a screening service for colorectal cancer from a pathology laboratory | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1080/00313020410001721519 | - |
pubs.publication-status | Published | - |
Appears in Collections: | Aurora harvest 4 Paediatrics publications |
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