Please use this identifier to cite or link to this item:
|Scopus||Web of Science®||Altmetric|
|Title:||Is the human chorionic gonadotrophin secreted by ectopic trophoblast different from that in normal intrauterine pregnancies?|
|Citation:||Fertility and Sterility, 1995; 64(4):724-729|
|Publisher:||American Fertility Society|
|Abstract:||<h4>Objective</h4>To determine whether different isoforms of hCG are secreted by trophoblast tissue from ectopic pregnancy (EP).<h4>Design</h4>Retrospective study of surgically confirmed EPs compared with normal pregnancies.<h4>Setting</h4>Teaching hospital in South Africa.<h4>Patients</h4>One hundred patients with EPs and 120 patients with normal pregnancies.<h4>Main outcome measures</h4>Isoforms of hCG were measured by specific immunoassays, lectin binding, and examination of disappearance rates of hCG after surgical clearance of EP.<h4>Results</h4>There were no obvious differences between the two types of pregnancy apart from a lower binding of beta-subunit immunoactivity to ricin 120. No clinically useful diagnostic measures to distinguish hCG from normal and EPs were found.<h4>Conclusions</h4>No obvious differences were found in the isoforms of hCG between the two types of pregnancy using these methods.|
|Keywords:||Trophoblasts; Blood; Urine; Humans; Pregnancy, Ectopic; Chorionic Gonadotropin; Lectins; Immunoassay; Postoperative Period; Chromatography; Retrospective Studies; Pregnancy; Isomerism; Reference Values; Female|
|Appears in Collections:||Obstetrics and Gynaecology publications|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.