Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/8543
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Relationships between age, dehydro-epiandrosterone sulphate and plasma glucose in healthy men |
Author: | Thomas, N. Morris, H. Scopacasa, F. Wishart, J. Need, A. |
Citation: | Age and Ageing, 1999; 28(2):217-220 |
Publisher: | OXFORD UNIV PRESS |
Issue Date: | 1999 |
ISSN: | 0002-0729 1468-2834 |
Abstract: | <h4>Background</h4>dehydro-epiandrosterone sulphate (DHEAS) has been reported to ameliorate diabetes mellitus in rats.<h4>Aim</h4>we investigated the relationships between plasma glucose, age, serum DHEAS and weight in healthy men.<h4>Methods</h4>we measured the serum DHEAS, fasting plasma glucose, plasma cortisol and body mass index in 169 subjects (mean age 46.5 years).<h4>Results</h4>there was a significant decline in serum DHEAS with age (P < 0.0001). Multiple linear regression showed significant relationships with plasma glucose for all measured variables. Age was not a significant determinant of plasma glucose after adjusting for log serum DHEAS, body mass index and log serum cortisol.<h4>Conclusions</h4>a lowered serum DHEAS is paralleled by an elevated plasma glucose within the normal reference interval, and this may contribute to the rise in fasting plasma glucose which occurs with ageing. |
Keywords: | Humans Dehydroepiandrosterone Sulfate Blood Glucose Body Mass Index Aging Adult Aged Aged, 80 and over Middle Aged Male |
DOI: | 10.1093/ageing/28.2.217 |
Published version: | http://dx.doi.org/10.1093/ageing/28.2.217 |
Appears in Collections: | Aurora harvest 4 Medicine publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.