Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/86936
Citations | ||
Scopus | Web of ScienceĀ® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Immobilisation versus immediate mobilisation after intrauterine insemination: randomised controlled trial |
Author: | Custers, I. Flierman, P. Maas, P. Cox, T. Van Dessel, T. Gerards, M. Mochtar, M. Janssen, C. van der Veen, F. Mol, B. |
Citation: | BMJ: British Medical Journal, 2009; 339(7729):1065-1067 |
Publisher: | BMJ Publishing Group |
Issue Date: | 2009 |
ISSN: | 1756-1833 1756-1833 |
Statement of Responsibility: | Inge M Custers, Paul A Flierman, Pettie Maas, Tessa Cox, Thierry J H M Van Dessel, Mariette H Gerards, Monique H Mochtar, Catharina A H Janssen, Fulco van der Veen and Ben Willem J Mol |
Abstract: | Objective To evaluate the effectiveness of 15 minutes of immobilisation versus immediate mobilisation after intrauterine insemination. Design Randomised controlled trial. Setting One academic teaching hospital and six non-academic teaching hospitals. Participants Women having intrauterine insemination for unexplained, cervical factor, or male subfertility. Interventions 15 minutes of immobilisation or immediate mobilisation after insemination. Main outcome measure Ongoing pregnancy per couple. Results 391 couples were randomised; 199 couples were allocated to 15 minutes of immobilisation after intrauterine insemination, and 192 couples were allocated to immediate mobilisation (control). The ongoing pregnancy rate per couple was significantly higher in the immobilisation group than in the control group: 27% (n=54) versus 18% (34); relative risk 1.5, 95% confidence interval 1.1 to 2.2 (crude difference in ongoing pregnancy rates: 9.4%, 1.2% to 17%). Live birth rates were 27% (53) in the immobilisation group and 17% (32) in the control group: relative risk 1.6, 1.1 to 2.4 (crude difference for live birth rates: 10%, 1.8% to 18%). In the immobilisation group, the ongoing pregnancy rates in the first, second, and third treatment cycles were 10%, 10%, and 7%. The corresponding rates in the mobilisation group were 7%, 5%, and 5%. Conclusion In treatment with intrauterine insemination, 15 minutes' immobilisation after insemination is an effective modification. Immobilisation for 15 minutes should be offered to all women treated with intrauterine insemination. Trial registration Current Controlled Trials ISRCTN53294431. |
Keywords: | Humans Infertility, Male Infertility, Female Insemination, Artificial Early Ambulation Pregnancy Rate Immobilization Pregnancy Supine Position Time Factors Adult Middle Aged Female Male Live Birth Young Adult Kaplan-Meier Estimate |
Rights: | Copyright status unknown |
DOI: | 10.1136/bmj.b4080 |
Published version: | http://dx.doi.org/10.1136/bmj.b4080 |
Appears in Collections: | Aurora harvest 7 Paediatrics publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.