Please use this identifier to cite or link to this item:
https://hdl.handle.net/2440/87412
Citations | ||
Scopus | Web of Science® | Altmetric |
---|---|---|
?
|
?
|
Type: | Journal article |
Title: | Control of gene expression in the P2-related template coliphages |
Author: | Kalionis, B. Dodd, I.B. Egan, J.B. |
Citation: | Journal of Molecular Biology, 1986; 191(2):199-209 |
Publisher: | Elsevier |
Issue Date: | 1986 |
ISSN: | 0022-2836 1089-8638 |
Statement of Responsibility: | Bill Kalionis, Ian B. Dodd, J.Barry Egan |
Abstract: | The PstI fragment (65.5% to 77.4%) of coliphage 186, known genetically to encode the major control genes, has been sequenced, and an analysis performed to assess coding capacity, transcription-translation signals, and to identify any other significant features. Our analysis indicates that the region encodes: (1) seven genes, including the int and cI genes, which overlap, the late control gene B, and two genes, named CP75 and CP76, encoding potential DNA-binding proteins; (2) a promoter pB and terminator tB for the rightward transcription of the B gene, and we predict the existence of this transcript in a lysogen; (3) a promoter pL and terminator tL for leftward transcription that encodes the int and cI genes, and represents the presumed lysogenic transcript; (4) a promoter pR for rightward transcription to give the presumed (early) lytic transcript that is overlapping and convergent with the lysogenic transcript; and finally (5), a potential operator site for repressor binding in the region of the pR promoter. Preliminary evidence is presented to support this analysis. |
Keywords: | Ribosomes Coliphages DNA, Viral Transcription, Genetic Gene Expression Regulation Binding Sites Base Sequence Repetitive Sequences, Nucleic Acid Promoter Regions, Genetic Terminator Regions, Genetic |
Rights: | © 1986 Academic Press, Inc. |
DOI: | 10.1016/0022-2836(86)90257-3 |
Published version: | http://dx.doi.org/10.1016/0022-2836(86)90257-3 |
Appears in Collections: | Aurora harvest 7 Biochemistry publications |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.